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Galisteo Basin is a region in north-central New Mexico 15 miles south of Santa Fe. The basin is fed by the Galisteo Creek. Northeast of Galisteo Basin lies the Sangre de Cristo Mountains and on the southwest lie the Sandia Mountains. Because of its location lying between mountain ranges and connecting the Rio Grande Valley with the Great Plains, the Galisteo Basin was used as a trade route by prehistoric and historic indigenous and later also by the Spanish explorers.